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RANKING · 2025 ESTIMATES · 46 SHOWN OF 46

Most population lost, South Carolina counties

South Carolina counties that lost the most residents from the 2020 census to 2025, by raw count of people rather than percentage. This list covers the 46 counties in South Carolina that qualify, ranked against each other statewide. The median across all 46 is +1,467. Biggest climber in the top 100 since 2020: Marlboro County, SC, up 11 places to #2.

Flip the list · Most population gained, US counties →
SAME RANKING BYCitiesStatesMetros
Most population lost by state
RANKPLACESTATEPOPPOPULATION CHANGEVS 2000
01▲6Williamsburg County, SCSC29,662-1,364−439%
02▲11Marlboro County, SCSC25,488-1,179+117%
03▼2Orangeburg County, SCSC83,177-1,046−115%
04▼1Marion County, SCSC28,242-941−160%
05Dillon County, SCSC27,458-834−152%
06▲3Lee County, SCSC15,730-801−148%
07▲5Allendale County, SCSC7,355-684+34%
08Fairfield County, SCSC20,340-608−152%
09▲1Bamberg County, SCSC12,796-515+111%
10▲5Sumter County, SCSC105,067-489−124%
11▲5Union County, SCSC26,799-445−2%
12▼1Hampton County, SCSC18,174-387−112%
13▼9Clarendon County, SCSC31,043-101−102%
14▼12Darlington County, SCSC62,888-17−100%
15▼1Barnwell County, SCSC20,653+64−98%
16▲3Calhoun County, SCSC14,188+69−97%
17▲1Abbeville County, SCSC24,836+541−77%
18▲4McCormick County, SCSC10,215+689−37%
19▲2Chester County, SCSC33,001+707−63%
20▲4Colleton County, SCSC39,382+778−80%
21▼1Saluda County, SCSC19,680+818−71%
22▲1Greenwood County, SCSC70,379+1,028−85%
23▲2Florence County, SCSC138,504+1,445−87%
24▼18Chesterfield County, SCSC44,740+1,467−65%
25▲1Newberry County, SCSC39,561+1,842−37%
26▲1Cherokee County, SCSC58,275+2,059−74%
27▲2Georgetown County, SCSC65,912+2,508−74%
28▼11Edgefield County, SCSC29,808+4,151−33%
29▼1Laurens County, SCSC71,848+4,309−62%
30▲2Oconee County, SCSC83,775+5,168−41%
31▼1Kershaw County, SCSC73,166+7,763−14%
32▲2Pickens County, SCSC139,198+7,794−54%
33▼2Jasper County, SCSC38,533+9,742+88%
34▼1Aiken County, SCSC181,515+12,707−41%
35Anderson County, SCSC219,930+16,212−21%
36▲2Dorchester County, SCSC178,397+16,857+26%
37Beaufort County, SCSC204,433+17,316−50%
38▼2Lancaster County, SCSC114,296+18,280+167%
39▲1Richland County, SCSC434,956+18,809−46%
40▼1Lexington County, SCSC317,588+23,597−51%
41▲2York County, SCSC306,887+24,797−25%
42▲2Charleston County, SCSC436,200+27,965+87%
43▼1Berkeley County, SCSC274,666+44,805+223%
44▼3Spartanburg County, SCSC380,857+52,860+96%
45Greenville County, SCSC583,125+57,591−3%
46Horry County, SCSC427,551+76,522+46%
SHOWING 1–46 OF 46

UPDATED 2026-09-11 · DATA: US CENSUS BUREAU POPULATION ESTIMATES